Australian researchers who were part of the Australian Islet Transplant Consortium have published their results on primary clinical outcomes from the Islet Transplantation program in the distinguished American Journal of Transplantation. This program was funded by the Department of Health and Ageing and administered by JDRF between 2005 and 2011.
Through the program, seventeen patients with severely unstable type 1 diabetes underwent an islet transplantation procedure.
The published report states that 82% of patients who received the transplantation achieved the primary goal of HbA1C levels of <7% and an absence of severe hypoglycaemic episodes. 53% of the recipients were insulin-independent for between 7-39 months, while 35% are still insulin-independent.
This study involved coordination through multiple centres across Australia and also supports what the authors call a ‘spoke and wheel’ model of islet transplant delivery, where the islet isolation process is carried out in specialised centres and shipped to point of care centres for transplantation.
The Islet Transplantation Program is particularly significant as it demonstrates the important contribution of Australian research to the global body of knowledge on this procedure, and JDRF’s role in bringing researchers together to deliver collaboration and progress.
If you would like to learn more about the types of patients that can be assisted by islet transplantation, please consult your endocrinologist.