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An American research team, partly funded by JDRF, have developed a hydrogel material that increased islet survival and function after transplantation in mice. The research, published in Science Advances, used a degradable hydrogel material combined with a protein called vascular endothelial growth factor (VEGF), to stimulate the growth of blood vessels into transplanted cells.

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 Two promising research projects have been targeted to receive contract seed funding grants, and will benefit from $350k in funding from the Type 1 Diabetes Clinical Research Network (T1DCRN), itself an innovative clinical research program led by JDRF Australia and funded by a Special Research Initiative through the Australian Research Council (ARC). These two projects […]

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A new technique that uses modified insulin and red blood cells to create a glucose-responsive insulin (GRI) delivery system has been developed by researchers from North Carolina State University and the University of North Carolina in the USA. The new technique effectively reduced blood sugar levels for more than 48 hours in mice that had type 1 diabetes. […]

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About one third of individuals with type 1 diabetes will develop kidney complications during their lifetime. Current treatment options for diabetic kidney disease can slow but not stop its progression, highlighting an urgent need for new approaches. Scientists at Boston’s Joslin Diabetes Center have revealed an unexpected route to slow the progression of diabetic kidney […]

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Six things to know about clinical trials
Published on May 19, 2017

This year, 20 May 2017 is International Clinical Trials Day, which aims to help raise awareness of the important role clinical trials play in public health and medical progress. Despite how critical these trials are to finding therapies to cure, prevent and treat type 1 diabetes (T1D), many people have questions about how clinical trials […]

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Lachie is not too busy
Published on May 4, 2017

Sixteen year old Lachlan has such a busy life that if we listed all his hobbies and interests here, we’d have no room for anything else. Alongside debating, art and technology, he’s an accomplished sportsman on field and in pool. He also does a little kite-surfing in his spare time. There’s one other interest that […]

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Securing the talented future of type 1 diabetes research
Published on April 27, 2017

JDRF is excited to announce that the JDRF/Macquarie Group Foundation Future Research Leaders Program (FRLP) pilot launched this month. Seven of the best and brightest rising stars of type 1 diabetes research, specialising in areas including glucose control, complications, immunology and beta cell biology are the first group to go through the program in its […]

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Stressed-out beta cells masters of own demise?
Published on March 30, 2017

The prevailing belief on how type 1 diabetes (T1D) develops is that the immune system mistakenly identifies insulin-producing beta cells as foreign, leading to their destruction. A new study published in Nature Medicine has found beta cells themselves may be causing the destructive immune response that leads to T1D. This is a relatively new concept […]

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There are a number of genes linked to type 1 diabetes (T1D), but not everyone with these genes will develop the condition. This suggests that there are likely environmental triggers that stimulate the development of T1D. The Environmental Determinants of Diabetes in the Young (TEDDY), a study part-supported by JDRF, investigates the environmental factors that […]

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‘Medicinal food’ diet counters onset of type 1 diabetes
Published on March 28, 2017

A JDRF-supported study has found – for the first time – that a diet that produces high amounts of the short-chain fatty acids acetate and butyrate provided a beneficial effect on the immune system and protected against type 1 diabetes. The specialised diet developed by CSIRO and refined by Monash University researchers uses resistant starches – […]

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