JDRF UK, Diabetes UK, and Tesco have announced $8.5 million of new funding for research into a type 1 diabetes (T1D) vaccine. The new funding provided by JDRF in conjunction with Diabetes UK and Tesco Supermarkets could produce the first working vaccines for T1D within the next generation. Four UK based projects will be funded:
Dr Hanna Skärstrand of Lund University Diabetes Centre in Malmö, Sweden, was the recent recipient of the JDRF and Macquarie Group Foundation International Diabetes Research Innovation Award. She speaks to JDRF today about her research.
JDRF-funded researchers in the US have developed a procedure to reverse or stop the type 1 diabetes autoimmune attack by boosting regulatory immune cells called Tregs. Described as the “master policemen of the immune system” by Dr Stephen Gitelman, Chief of the Pediatric Endocrine Division of the University of California San Francisco, these Treg cells […]
Researchers from the US and the UK have located a previously unidentified pathway buried deep within the brain that helps to sense blood glucose levels. The hormone cholecystokinin (CCK) was found in the parabrachial nucleus region of the brain. It plays a crucial role in sensing hypoglycaemia and initiating a series of responses in the […]
US-based researchers have genetically engineered a bacteria normally found in yoghurt to help control blood glucose levels in diabetic rats. The researchers engineered this bacteria (probiotic), known as Lactobacillus gasseri, to secrete a hormone called glucagon-like peptide-1 (GLP-1). When this was fed to diabetic rats, the probiotic caused cells in the upper intestine to behave […]
Thanks to all those who took an interest in yesterday’s media about progress in the Artificial Pancreas. We note that some of the media coverage wasn’t clear about whether this announcement represents a complete Artificial Pancreas. The facts are that research progress has been made and as a result, a more advanced insulin pump is […]
Access to life-changing technology is now a step closer for Australians with type 1 diabetes. Four-year-old Xavier Hames (diagnosed at 22 months) has become the first child in the world to receive breakthrough insulin pump technology to help manage type 1 diabetes. This new technology has been researched and tested through a series of clinical […]
American researchers from Harvard University have been able to engineer stem cells to have a “homing” molecule, which steers them towards the pancreas after being injected into the body. Mesenchymal stem cells (MSCs) are a type of adult stem cell that have strong effects on reducing inflammation and immune moderation.
Tight control of blood glucose levels (BGLs) have been shown to improve the lifespan of people with type 1 diabetes in a thirty-year longitudinal clinical study. Beginning in 1983, the Diabetes Control and Complications Trial (DCCT) and the follow-up Epidemiology of Diabetes Control and Complications (EDIC) study included 1,441 people with T1D between ages 13 […]
JDRF partner Viacyte, a US-based regenerative medicine company, has successfully transplanted human pancreatic tissue into mice without immune rejection of the tissue. In this new preliminary study, stem cell-derived immature pancreatic cells were transplanted into mice that had their own beta-cells chemically destroyed. The mice were treated with drugs for two weeks that block specific […]