New discovered pathway keeps immune system in check
Published on May 1, 2015

Discovery of an immune system molecule could help to boost the immunity of people with a predisposition to type 1 diabetes. JDRF researchers found that high levels of this molecule known as PEPITEM could restore normal immune T cell function and therefore reverse or stop the T1D autoimmune attack. These researchers identified that PEPITEM controls […]

Australia’s largest study on the causes of T1D receives $8m boost
Published on April 27, 2015

JDRF Australia has today announced that a new $8 million partnership with The Leona M. and Harry B. Helmsley Charitable Trust, for investment into the Australian Type 1 Diabetes Clinical Research Network (T1DCRN), a JDRF Australia initiative. This partnership will support Environmental Determinants of Islet Autoimmunity (ENDIA), a ground-breaking study to help solve the mystery […]

Learn More: JDRF Encapsulation Research
Published on April 20, 2015

JDRF’s research strategy focuses on a number of key areas that are most likely to deliver new therapies and treatments, and a cure, to people with type 1 diabetes in the most efficient and effective way in the short and long term. One of these key research areas is in the field of encapsulation – […]

Nanoparticles re-educating the immune system
Published on April 17, 2015

JDRF partner Selecta is developing a new technology that could lead to a vaccine for T1D. In an article recently published in Proceedings of the National Academy of Sciences, researchers described the technology which uses nanoparticles to stop the autoimmune attack on insulin-producing beta cells in the pancreas.

$8.5m investment in a T1D vaccine
Published on March 23, 2015

JDRF UK, Diabetes UK, and Tesco have announced $8.5 million of new funding for research into a type 1 diabetes (T1D) vaccine. The new funding provided by JDRF in conjunction with Diabetes UK and Tesco Supermarkets could produce the first working vaccines for T1D within the next generation. Four UK based projects will be funded:

JDRF-funded trial to reverse type 1 diabetes using Treg cells
Published on March 9, 2015

JDRF-funded researchers in the US have developed a procedure to reverse or stop the type 1 diabetes autoimmune attack by boosting regulatory immune cells called Tregs. Described as the “master policemen of the immune system” by Dr Stephen Gitelman, Chief of the Pediatric Endocrine Division of the University of California San Francisco, these Treg cells […]

Hidden neuro-hormone helps control hypoglycaemia
Published on February 16, 2015

Researchers from the US and the UK have located a previously unidentified pathway buried deep within the brain that helps to sense blood glucose levels. The hormone cholecystokinin (CCK) was found in the parabrachial nucleus region of the brain. It plays a crucial role in sensing hypoglycaemia and initiating a series of responses in the […]

Probiotics could help manage BGLs
Published on February 16, 2015

US-based researchers have genetically engineered a bacteria normally found in yoghurt to help control blood glucose levels in diabetic rats. The researchers engineered this bacteria (probiotic), known as Lactobacillus gasseri, to secrete a hormone called glucagon-like peptide-1 (GLP-1).  When this was fed to diabetic rats, the probiotic caused cells in the upper intestine to behave […]

JDRF statement on new technology announced on 21 January
Published on January 22, 2015
Research Progress

Thanks to all those who took an interest in yesterday’s media about progress in the Artificial Pancreas. We note that some of the media coverage wasn’t clear about whether this announcement represents a complete Artificial Pancreas. The facts are that research progress has been made and as a result, a more advanced insulin pump is […]