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JDRF-funded trial to reverse type 1 diabetes using Treg cells
Published on March 9, 2015

JDRF-funded researchers in the US have developed a procedure to reverse or stop the type 1 diabetes autoimmune attack by boosting regulatory immune cells called Tregs. Described as the “master policemen of the immune system” by Dr Stephen Gitelman, Chief of the Pediatric Endocrine Division of the University of California San Francisco, these Treg cells […]

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Hidden neuro-hormone helps control hypoglycaemia
Published on February 16, 2015

Researchers from the US and the UK have located a previously unidentified pathway buried deep within the brain that helps to sense blood glucose levels. The hormone cholecystokinin (CCK) was found in the parabrachial nucleus region of the brain. It plays a crucial role in sensing hypoglycaemia and initiating a series of responses in the […]

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Probiotics could help manage BGLs
Published on February 16, 2015

US-based researchers have genetically engineered a bacteria normally found in yoghurt to help control blood glucose levels in diabetic rats. The researchers engineered this bacteria (probiotic), known as Lactobacillus gasseri, to secrete a hormone called glucagon-like peptide-1 (GLP-1).  When this was fed to diabetic rats, the probiotic caused cells in the upper intestine to behave […]

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JDRF statement on new technology announced on 21 January
Published on January 22, 2015
Research Progress

Thanks to all those who took an interest in yesterday’s media about progress in the Artificial Pancreas. We note that some of the media coverage wasn’t clear about whether this announcement represents a complete Artificial Pancreas. The facts are that research progress has been made and as a result, a more advanced insulin pump is […]

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Access to life-changing technology is now a step closer for Australians with type 1 diabetes. Four-year-old Xavier Hames (diagnosed at 22 months) has become the first child in the world to receive breakthrough insulin pump technology to help manage type 1 diabetes. This new technology has been researched and tested through a series of clinical […]

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Homing stem cells cure type 1 diabetes in mice
Published on January 20, 2015

American researchers from Harvard University have been able to engineer stem cells to have a “homing” molecule, which steers them towards the pancreas after being injected into the body. Mesenchymal stem cells (MSCs) are a type of adult stem cell that have strong effects on reducing inflammation and immune moderation.

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BGL control helps improve lifespan for people with T1D
Published on January 14, 2015

Tight control of blood glucose levels (BGLs) have been shown to improve the lifespan of people with type 1 diabetes in a thirty-year longitudinal clinical study. Beginning in 1983, the Diabetes Control and Complications Trial (DCCT) and the follow-up Epidemiology of Diabetes Control and Complications (EDIC) study included 1,441 people with T1D between ages 13 […]

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New temporary drugs to replace immunosuppressant drugs
Published on December 22, 2014

JDRF partner Viacyte, a US-based regenerative medicine company, has successfully transplanted human pancreatic tissue into mice without immune rejection of the tissue. In this new preliminary study, stem cell-derived immature pancreatic cells were transplanted into mice that had their own beta-cells chemically destroyed. The mice were treated with drugs for two weeks that block specific […]

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JDRF-funded researcher part of international study
Published on December 17, 2014

JDRF-funded Australian scientist Professor Nathan Efron from the Queensland University of Technology, along with other international researchers and research institutions, has been awarded a combined US$1.1 million from the National Institutes of Health (NIH) in the US. This international multi-site multi-disciplinary project grant is for a new study entitled “’Multinational Collaborative Evaluation of Corneal Confocal […]

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